Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes

Table 7

The effect of test compounds on hematological parameters in normal and tumour bearing mice.

Name of experiment	HB level; g/dL	RBC; cell/mL	WBC (TC); cell/mL	Lymphocyte %	Neutrophil %	Monocyte %
Normal mice	13.65 ± 0.4	(7.96 ± 0.57) × 10^9	(6.35 ± 0.26) × 10^6	71.25 ± 0.91	19.19 ± 0.28	8.93 ± 0.23
N + A	12.25 ± 0.17	(6.16 ± 0.16) × 10^9	(10.76 ± 0.17) × 10^6	75.00 ± 0.83	21.79 ± 0.38	3.10 ± 0.34
N + B	10.23 ± 0.13	(5.93 ± 0.22) × 10^9	(16 ± 0.23) × 10^6	72.10 ± 0.34	26.23 ± 0.24	1.73 ± 0.17
N + C	11.89 ± 0.26	(6.33 ± 0.19) × 10^9	(14 ± 0.23) × 10^6	73.47 ± 0.83	24.21 ± 0.16	2 ± 0.21
EAC (mice)	7.11 ± 0.23	(2.40 ± 0.10) × 10^9	(25.63 ± 0.18) × 10^6	43.36 ± 0.43	38.23 ± 0.37	10 ± 0.28
EAC + A	11.25 ± 0.23	(6.04 ± 0.21) × 10^9	(9.19 ± 0.36) × 10^6	60.25 ± 0.68	26.65 ± 0.18	8 ± 0.86
EAC + B	10.14 ± 0.18	(5.62 ± 0.27) × 10^9	(14.82 ± 0.41) × 10^6	51.87 ± 0.78	34.11 ± 0.22	6.12 ± 0.92
EAC + C	10.34 ± 0.10	(5.89 ± 0.29) × 10^9	(12.67 ± 1.40) × 10^6	57.68 ± 1.37	33.20 ± 2.8	8.10 ± 3.10

A = K[Cu(SB-1)(SCN)], B = [Cu(SB-2)NN], NN = 2-aminopyridine, and C = [Cu(SB-2)(NN)], NN = 2-phenylenediamine.