Research Article
β-Carboline Silver Compound Binding Studies with Human Serum Albumin: A Comprehensive Multispectroscopic Analysis and Molecular Modeling Study
Table 5
Noncovalent interactions of compound 2 with the HSA binding site III.
| | Name | Distance (Å) | Category | Type |
| | Compound 2: H4-GLY189:O | 2.73 | Hydrogen bond | Conventional | | LYS190-compound 2 | 4.88 | Electrostatic | π-Cation | | Compound 2: O3-PHE157 | 3.39 | Electrostatic | π-Anion | | TYR161-compound 2 | 4.29 | Hydrophobic | π-π Stacked | | TYR161-compound 2 | 4.72 | π-π Stacked | | Compound 2-A: TYR161 | 3.91 | π-π Stacked | | Compound 2-A: ILE142 | 3.64 | π-Alkyl | | Compound 2-A: ILE142 | 4.98 | π-Alkyl | | Compound 2-A: LEU135 | 5.43 | π-Alkyl | | Compound 2-A: ALA158 | 4.91 | π-Alkyl | | Compound 2-A: LYS190 | 4.11 | π-Alkyl | | Compound 2-A: LYS190 | 3.09 | π-Alkyl | | Compound 2-A: LYS190 | 3.21 | π-Alkyl |
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