Glutaraldehyde-Polymerized Hemerythrin: Evaluation of Performance as an Oxygen Carrier in Hemorrhage Models

Table 2

Summary of histological findings of transfusion experiments in the present study.

Groups

Liver

Lungs

Kidneys

GVD

DG

N

S

K

ED

S

N

GVD

DG

TL

S

M

USD

TD

C

—

—

—

—

—

—

—

—

—

—

—

—

—

—

H

—

—

—

—

+

—

—

—

—

—

—

—

—

—

+

P

—

VD++

—

—

—

—

—

—

—

—

—

+/−

—

—

pHr

+++

++

—

—

—

—

—

VD+

—

—

—

—

—

pHrHSA

++

VD++

—

—

—

—

—

+/−

++

—

—

—

++

GVD: granular and vacuolar degeneration, DG: degeneration, VD/GD: vacuolar degeneration/granular degeneration, N: necrosis, S: stasis, K: Kupffer cells, ED: edema, TL: tubular lesions, M: mesangial proliferation, USD: urinary space dilation, TD: tubular dilation; blank: no changes/not present, +/−: slight/absent changes, +: slight changes, ++: moderate changes, and +++: prominent changes.