[Retracted] Fluorescent Carbon Dot-Supported Imaging-Based Biomedicine: A Comprehensive Review

Figure 6

Fluorescence imaging-guided therapy using CDs. (a) Schematic of FL imaging-guided therapeutics of liver cancer using FA-CDs-DOX. Adapted with permission from Ref. [182]. (b) Demonstration of ultrasound-enhanced theranostics of multidrug-resistant tumors using G5-TPGS@y-CDs)-DOX drug-loaded CD/dendrimer nanohybrids. Adapted with permission from Ref. [178]. (c) (A) Therapeutic schedule of (G5-TPGS@y-CDs)-DOX and ultrasound-targeted microbubble destruction (UTMD) treatment in vivo. (B) Tumor volumes, (C) body weights, and (D) survival rate of mice after intravenous injection periods of different groups (saline, free DOX, (G5-(m)PEG@y-CDs)-DOX, (G5-TPGS@y-CDs)-DOX, or (G5-TPGS@y-CDs)-DOX + UTMD) showed the effective chemotherapy of tumors. Adapted with permission from Ref. [178]. (d) In vivo FL images of glioma-bearing mice after intravenous injection of saline and HCCDs, and ex vivo images of major organs after administration under 465 nm excitation displayed the accumulation of HCCDs in the tumor region for the effective FL imaging-guided PPT of glioma. Adapted with permission from Ref. [189].