New Organotin (IV) Compounds Derived from Dehydroacetic Acid and Thiosemicarbazides: Synthesis, Rational Design, Cytotoxic Evaluation, and Molecular Docking Simulation

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Temperature (°C)</td><td class="align_center">Kb (M)</td><td class="align_center">ΔGb (kcal·mol−1)</td><td class="align_center">ΔHb (kcal·mol−1)</td><td class="align_center">−TΔSb (kcal·mol−1)</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">25</td><td class="align_center">4.5 × 104 ± 5.35 ×103</td><td class="align_center">−6.3474</td><td class="align_center">−3.775 ± 0.272</td><td class="align_center">−2.573</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Thermodynamic parameters of affinity assay of compound 1c with ss-DNA.</div>

Bioinorganic Chemistry and Applications

tab5

Table 5

Table 5: New Organotin (IV) Compounds Derived from Dehydroacetic Acid and Thiosemicarbazides: Synthesis, Rational Design, Cytotoxic Evaluation, and Molecular Docking Simulation 

Table 5 | New Organotin (IV) Compounds Derived from Dehydroacetic Acid and Thiosemicarbazides: Synthesis, Rational Design, Cytotoxic Evaluation, and Molecular Docking Simulation 