Research Article
Synthesis and Characterization of Paclitaxel-Loaded Silver Nanoparticles: Evaluation of Cytotoxic Effects and Antimicrobial Activity
Table 5
Antimicrobial activity results of the AgNPs and AgNPs-PTX.
| | Microorganisms (bacteria and yeasts) | MIC (μg/mL) AgNPs | MIC (μg/mL) AgNPs-PTX | MIC (μg/mL) antibiotics | Antibiotics used |
| | Escherichia coli | 100 | 25 | 8 | Amoxicillin | | Klebsiella pneumoniae | 100 | 50 | 16 | Piperacillin/Tazobactam | | Acinetobacter baumannii | 100 | 50 | 64 | Cefepime | | Pseudomonas aeruginosa | 25 | 12.5 | 16 | TMP-STX | | Staphylococcus aureus | 50 | 25 | 64 | Chloramphenicol | | Methicillin-resistant Staphylococcus aureus (MRSA) | 25 | 12.5 | 64 | Ciprofloxacin | | Enterococcus faecalis | 50 | 12.5 | 8 | Chloramphenicol | | Bacillus cereus | >200 | >200 | 1 | Linezolid | | Candida albicans | >200 | >200 | 0.25 | Fluconazole | | Candida tropicalis | >200 | >200 | 0.25 | Fluconazole |
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The data obtained were studied as n = 3. Effective (MIC ≤ 100 μg/mL), moderate (100 < MIC ≤ 625 μg/mL), and weak (MIC > 625 μg/mL).
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