Anti-MMP-9 antibody attenuated neutrophil-mediated increase in permeability. The neutrophils were pre-treated with either anti-MMP-9 antibody or control antibody followed by incubation with explants for 3 hours at . The apparent permeability was determined by [3H]-mannitol flux and the data were presented as the fold increase in permeability relative to vehicle-treated samples. *represents .