Optimal Fluxes, Reaction Replaceability, and Response to Enzymopathies in the Human Red Blood Cell

Figure 3

hRBC’s structural reaction replaceability map. Thick black arrows denote unreplaceable reactions (group (b) above); thick white-filled arrows denote reversible reactions that can be replaced only in the direction indicated by the arrow (group (c)); all other reactions are fully replaceable (group (a)).