Diclofenac-Induced Apoptosis in the Neuroblastoma Cell Line SH-SY5Y: Possible Involvement of the Mitochondrial Superoxide Dismutase
Figure 4
Effect of diclofenac on SOD2 activity. (a) SH-SY5Y cells were treated with vehicle alone or 150 M diclofenac for the indicated times. Total cell extracts were fractionated on a nondenaturing polyacrylamide gel and SOD2 activity was evaluated as described in Section 2.10. (b) Densitometry evaluation of three independent experiments; * compared to untreated cells.
