Research Article
Urinary Elimination of Coproporphyrins Is Dependent on ABCC2 Polymorphisms and Represents a Potential Biomarker of MRP2 Activity in Humans
Table 1
Primers used for genotyping ABCC2 (MRP2) polymorphisms.
| | SNP | Reference | Primer sequence (5′→3′) | Fragment size, bp |
| | ABCC2 5′UTR | rs717620 | F CCTTTACGGAGAACATCAGA | 252 | | −24C/T | | R TTCTGGTTCTTGTTGGTGAC | | | ABCC2 exon 10 | rs2273697 | F GTGCCTTGGAGAAGCTGTGT | 478 | | 1249G/A | | R TTGCCCAAACTCCCATTAAG | | | ABCC2 exon 25 | rs17216324 | F GTAAGCTGTGCCCATCAAGG | 383 | | 3563T/A | | R CCTCCCACCGCTAATATCAA | | | ABCC2 exon 28 | rs3740066 | F GAGTCCTGGGTGGACTGTTC | 291 | | 3972C/T | | R CCAGCTGCTCTCCACTCTGT | | | ABCC2 exon 32 | rs8187710 | F AAATGCCTAGACTTGAGATGCTG | 449 | | 4544G/A | | R CGTGAAATTCAGGACAGTGG | |
|
|
