Polyunsaturated fatty acid content particularly ALA, and eicosapentaenoic acid (EPA) was elevated after supplementation with milled chia. The result was in agreement with previous studies conducted in hens, rats, and rabbits.
Single blinded with 76 subjects (placebo 37; chia seed 39)
25 g chia seed in 250 mL water twice/day
Although Nieman et al. have hypothesized that the high dietary fiber and ALA content in chia can promote human weight loss and reduce disease risk factors related to heart disease and obesity, no significant results on weight loss and disease risk factors even though the plasma level of ALA increased.