The Effects of Pterostilbene on Neutrophil Activity in Experimental Model of Arthritis

<table>Priming of neutrophils in arthritic rats. Arthritic animals (AA) showed significantly higher spontaneous (0) and PMA-stimulated ROS production (<svg height="13.95" id="M6" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 73.300003 13.95" width="73.300003" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> AA versus control). PMA caused dose-dependent increase in ROS production which was significantly higher in comparison with spontaneous ROS production in arthritic rats (<svg height="15.775" id="M7" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 75.449997 15.775" width="75.449997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> AA-stimulated versus AA-spontaneous). Values are mean ± SEM, <svg height="11.125" id="M8" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 44.400002 11.125" width="44.400002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>. RLU<svg height="7.9250002" id="M9" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.1 7.9250002" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>s: relative light units multiplied by time (seconds).</table>

BioMed Research International

fig3

Figure 3

Figure 3: The Effects of Pterostilbene on Neutrophil Activity in Experimental Model of Arthritis 