Dantrolene-Induced Inhibition of Skeletal L-Type Ca2+ Current Requires RyR1 Expression
Figure 4
Dantrolene does not affect the recovery of the fast skeletal muscle Na+ current from inactivation. Representative recordings of skeletal Na+ current elicited by two 20 ms depolarizations from −80 mV to 0 mV separated by time intervals ranging from 5 ms to 55 ms in 10 ms increments are shown for untreated control myotubes (a) and myotubes exposed to 10 M Dantrolene (b). (c) Summary of results.
