Risk Factors for the First Episode of Klebsiella pneumoniae Resistant to Carbapenems Infection in Critically Ill Patients: A Prospective Study

Table 2

Clinical characteristics of participants in the ICU before KPRC or non-MDR infection.

	KPRC; (𝑁=25)	𝑃^∗	Non MDR bacterial infection; (𝑁=18)	𝑃^#	No bacteria group; (𝑁=39)	𝑃^#
MV duration (days)	10 (5, 19)	0.003	5 (2, 8)	0.005	7 (4, 11)	0.021
Surgical operation	15 (60)	0.852	12 (66.7)	0.735	23 (59)	1.0
Invasive procedures	6 (24)	0.044	1 (5.6)	0.209	2 (5.1)	0.048
Catheterization of urinary bladder prior ICU admission	1 (4)	0.850	1 (5.6)	1.0	1 (2.6)	1.0
Tracheotomy	7 (28)	0.403	2 (11.1)	0.283	8 (20.5)	1.0
Sedation	22 (88)	0.252	18 (100)	0.252	37 (95)	0.371
CVVHDF use	4 (16)	0.781	2 (11.1)	1.0	4 (10.3)	0.701
CVVHDF duration (days)	0 (0, 0)	0.179	0 (0, 0)	0.396	0 (0, 0)	0.271
Corticosteroids (mg of hydrocortisone/day)	0 (0, 1)	0.936	0 (0, 0)	1.0	0 (0, 0)	1.0

Data are presented as median (25% and 75% quartiles) or 𝑛 (%); KPRC: Klebsiella pneumonia resistant to carbapenems; MDR: multidrug resistant bacteria; MV: mechanical ventilation; ICU: Intensive Care Unit; CVVHDF: Continuous veno-venous hemodiafiltration; invasive procedures, gastroscopy, colonoscopy, or bronchoscopy; 𝑃^∗: comparison between three groups; 𝑃^#: KPRC versus non-MDR group, KPRC versus no bacteria group. Results are by univariate analysis.