The Conyza triloba Extracts with High Chlorophyll Content and Free Radical Scavenging Activity Had Anticancer Activity in Cell Lines

Table 5

Determination of anti-mutagenic activity of plant extracts in Salmonella typhimurium TA1535 against benzo[a]pyrene (B[a]P; 20 μM) in presence of S9 mix.

Treatment	B[a]P mutagenicity at plant extract concentrations; (revertant colonies/plate; mean ± SEM (% reduction in B[a]Pmutagenicity))
	Preexposure*		Coexposure*
	1 mg/mL	5 mg/mL	1 mg/mL	5 mg/mL
B[a]P	324.3 ± 21.5
I	147.7 ± 5.9 (63)^a	109.0 ± 10.2 (77)^a,b	160.7 ± 10.5 (59)^a	150.0 ± 7.1 (62)^a
II	63.7 ± 11.1 (93)^a	52.7 ± 6.1 (97)^a	97.7 ± 6.7 (81)^a	93.7 ± 9.2 (83)^a
III	55.0 ± 4.7 (96)^a	63.3 ± 7.5 (93)^a	98.0 ± 7.8 (81)^a	91.7 ± 4.7 (83)^a
IV	54.0 ± 2.9 (97)^a	47.3 ± 3.7 (99)^a	95.3 ± 3.5 (82)^a	90.7 ± 9.3 (84)^a
V	92.3 ± 4.1 (83)^a	58.3 ± 7.3 (95)^a,b	111.7 ± 5.8 (76)^a	105.3 ± 8.7 (78)^a

∗Plant extracts were incubated with bacteria either 30 minutes before B[a]P (preexposure) or incubated with the bacteria and B[a]P (coexposure). The spontaneous revertant colonies were 45.0 ± 4.9. ^aSignificant (P < 0.05) reduction (% of inhibition of mutagenicity indicated in parentheses) from revertant colonies seen with B[a]P. ^bSignificant difference (P < 0.05) between plant extract concentrations.