Formulation and Optimization of Polymeric Nanoparticles for Intranasal Delivery of Lorazepam Using Box-Behnken Design: <i>In Vitro</i> and <i>In Vivo</i> Evaluation

<table>FTIR spectra of Lzp-PLGA-NPs (a), placebo (b), and pure lorazepam (c).</table>

BioMed Research International

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Figure 9

Figure 9: Formulation and Optimization of Polymeric Nanoparticles for Intranasal Delivery of Lorazepam Using Box-Behnken Design: <i>In Vitro</i> and <i>In Vivo</i> Evaluation 

Figure 9 | Formulation and Optimization of Polymeric Nanoparticles for Intranasal Delivery of Lorazepam Using Box-Behnken Design: In Vitro and In Vivo Evaluation 