Research Article

[Retracted] Downregulation of MDR1 Gene by Cepharanthine Hydrochloride Is Related to the Activation of c-Jun/JNK in K562/ADR Cells

Figure 4

Effects of the JNK inhibitor SP600125 (2.0 μM) on CH-induced downregulation of P-gp expression by Western blot analysis in K562/ADR cells (1 × 106). CH-induced downregulation of P-gp expression was abolished partly when combined with SP600125 (2.0 μM).