Comparative Assessment of Lymph Node Micrometastasis in Cervical, Endometrial and Vulvar Cancer: Insights on the Real Time qRT-PCR Approach versus Immunohistochemistry, Employing Dual Molecular Markers

Table 1

Clinicopathological data of the series of 46 patients tested for micrometastases.

Patient code	Location	Histological classification	Stage	Grade	Lymph nodes (positive/total)
IC5	Cervix	Squamous cell carcinoma keratinizing	Ib1	1	0/40
IC6	Cervix	Squamous cell carcinoma keratinizing	Ib1	3	0/47
IC8	Cervix	Squamous cell carcinoma keratinizing	Ib2	2	8/48
IC9	Cervix	Squamous cell carcinoma keratinizing	Ib2	1	2/19
IC10	Cervix	Squamous cell carcinoma keratinizing	Ib1	2	0/34
IC11	Cervix	Villoglandular papillary adenocarcinoma	Ib1	2	0/29
IC12	Cervix	Squamous cell carcinoma keratinizing	Ib1	2	0/53
IC14	Cervix	Squamous cell carcinoma keratinizing	Ia1	In situ	0/18
IC15	Cervix	Squamous cell nonkeratinizing carcinoma	Ib1	2	0/21
IC16	Cervix	Squamous cell carcinoma papillary basaloid	Ib1	1	0/41
IC17	Cervix	Squamous cell carcinoma keratinizing	IIa1	3	0/43
IC18	Cervix	Squamous cell carcinoma keratinizing	Ia1	2	0/31
IC19	Cervix	Squamotransitional papillary carcinoma	Ib1	2	0/30
IC20	Cervix	Adenosquamous carcinoma	Ib1	2	0/40
IC22	Cervix	Squamous cell carcinoma keratinizing	Ib1	2	0/19
IC23	Cervix	Squamous cell carcinoma keratinizing	IIa1	2	0/60
IC24	Cervix	Squamous cell carcinoma keratinizing	IIa1	2	1/28
IC25	Cervix	Squamous cell carcinoma keratinizing	Ia2	2	0/42
IC27	Cervix	Squamous cell carcinoma keratinizing	Ib1	2	0/26
IE1	Uterus	Endometrioid adenocarcinoma	Ib	1	0/11
IE6	Uterus	Endometrioid adenocarcinoma	Ib	2	0/22
IE10	Uterus	Endometrioid adenocarcinoma	Ib	1	0/6
IE11	Uterus	Endometrioid adenocarcinoma	Ia	2	0/28
IE12	Uterus	Endometrioid adenocarcinoma	IIIc	2	3/25
IE13	Uterus	Adenocarcinoma endometrioid and mucinous	Ib	2	1/5
IE14	Ovary and uterus	Adenocarcinoma endometrioid with squamous metaplasia	Ib	2	0/29
IE15	Uterus	Endometrioid adenocarcinoma	0	0	0/23
IE16	Uterus	Clear cell adenocarcinoma	Ib	3	0/17
IE17	Uterus	Endometrioid adenocarcinoma	Ib	1	0/16
IE18	Uterus	Endometrioid adenocarcinoma	Ib	2	0/3
IE19	Uterus	Mucinous adenocarcinoma	Ib	2	0/16
IE20	Ovary and uterus	Endometrioid adenocarcinoma	Ib	1	0/12
IE23	Uterus	Endometrioid adenocarcinoma	Ia	1	0/4
IE24	Uterus	Malignant Müllerian mixed tumor	Ib	0	0/10
IE25	Uterus	Adenocarcinoma serous, papillary, and clear cell	Ib	3	0/56
IE27	Uterus	Endometrioid adenocarcinoma	IIIa	2	0/33
IE31	Uterus	Clear cell adenocarcinoma	IIIc	2	1/5
IV4	Vulva	Squamous cell carcinoma keratinizing	II	1	0/42
IV5	Vulva	Squamous cell carcinoma keratinizing	IIIb	3	3/35
IV6	Vulva	Squamous cell carcinoma keratinizing	IIIb	2	4/25
IV9	Vulva	Squamous cell carcinoma keratinizing	III	2	3/35
IV11	Vulva	Squamous cell carcinoma keratinizing	Ib	1	0/42
IV12	Vulva	Acrochordon verrucous	II	2	0/23
IV13	Vulva	Squamous cell carcinoma keratinizing	Ib	1	0/42
IV15	Vulva	Squamous cell carcinoma keratinizing	IIIb	1	1/30
IV16	Vulva	Squamous cell carcinoma keratinizing	IIIb	3	1/17

IC: cervical carcinoma, IE: endometrial carcinoma, IV: vulvar carcinoma. Diagnosis for patient IE15 was established following dilation and curettage for uterine polyps.