Clinical Study

The Positive Effects of One-Hour Intravenous Administration of Bortezomib on Peripheral Neuropathy in Multiple Myeloma Patients

Table 4

Adverse events.

All grades Grade ≥ 3

Anorexia15(65%)0
Peripheral sensory neuropathy13(57%)1(4%)
Upper respiratory infection11(48%)1(4%)
Nausea11(48%)0
Fatigue8(35%)0
Gastrointestinal pain7(31%)0
Diarrhea7(31%)1(4%)
Skin rash5(22%)0
Dizziness5(22%)0
Constipation5(22%)0
Headache4(17%)0
Vomiting3(13%)0
Cramping3(13%)0
Myalgia3(13%)0
Insomnia3(13%)0
Neuralgia caused by herpes zoster3(13%)0
Fever3(13%)0
Dyspnea3(13%)0
Noncardiac chest pain3(13%)0
Hematology laboratory data
 Hemoglobin11(48%)9(39%)
 White blood cell count19(83%)8(35%)
 Absolute neutrophil count17(74%)10(43%)
 Platelets20(87%)6(26%)