Protective Effect of a Lipid-Based Preparation from Mycobacterium smegmatis in a Murine Model of Progressive Pulmonary Tuberculosis

Figure 3

Area of pneumonia in the lungs of mice infected with Mtb H37Rv after two months of inoculation. PBS (PBS), BCG (BCG Phipps), LMs (lipid extract from Ms), and LMs-AL (LMs adjuvanted with alum). The morphometric study was carried out with light microscopy using Leica Q-win System Software. Results are presented as mean ± SD. One-way ANOVA and Multiple Range tests were used to analyze the data. Different letters denote significant statistical differences between the groups ().