Inhibitory Effects of Edaravone in β-Amyloid-Induced Neurotoxicity in Rats

Figure 2

Inhibition of the action of Aβ _1–40 by EDA in hippocampal neurons. (a) EDA reduced the amplitude of 𝐼_Ca induced by Aβ _1–40. a, Aβ _1–40; B, EDA (100 μmol/L). (b) Summary of inhibition (percent) of 𝐼_Ca by EDA at concentrations of 1, 10, 100, and 300 μmol/L. **𝑃<0.01 versus control.

(a)

(b)