Effects of Shiga Toxin Type 2 on Maternal and Fetal Status in Rats in the Early Stage of Pregnancy
Figure 3
Histological evaluation of the uteroplacental unit.Alterations in the histoarchitecture (black arrowheads (b)) and isolated focus of hemorrhage (red arrow (b)) were observed in Stx2-treated rats. High magnification showed trophoblast fragmented nuclei (black arrows (d)) and necrosis area (black asterisk (d)). Normal tissues were observed in control rats ((a) and (c)). Black squares in (a) and (b) indicate the magnification zone corresponding to (c) and (d), respectively. (a, b): ×40; (c, d): ×200. D, decidua; G, trophoblast giant cells; L, labyrinth; S, spongious layer.
