Hypofractionated High-Dose Irradiation with Positron Emission Tomography Data for the Treatment of Glioblastoma Multiforme

Figure 6

Representative cases of cerebrospinal fluid dissemination: 55-year-old man with GBM. Before Hypo-IMRT, an enhanced tumor was demonstrated in the left temporal lobe on T1-weighted magnetic resonance imaging (MRI) (a). ¹¹C-Methionine positron emission tomography (MET-PET) demonstrated a MET high-uptake region in the left temporal lobe (b). 20 months after Hypo-IMRT, the enhanced tumor was decreased in size (c), and the MET high-uptake region could not be detected distinctly (d), although disseminated lesion was observed around the left lateral ventricle (e).

(a)

(b)

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(d)

(e)