Prophylactic Efficacy of Melatonin on Cyclophosphamide-Induced Liver Toxicity in Mice

Figure 3

Pretreated animals with 20 mg/kg of melatonin for 7 days before CP administration; section in the liver of a mouse pretreated with 20 mg/kg of melatonin along with CP showing normal hepatocyte (red arrow), semicongested sinusoidal space (yellow arrow), and portal space with mild-to-moderate inflammation (blue arrow) (hematoxylin- and eosin-stained paraffin sections; H&E ×400).