Human Schwann Cells Seeded on a Novel Collagen-Based Microstructured Nerve Guide Survive, Proliferate, and Modify Neurite Outgrowth
Figure 8
TPSLM images of hSCs in the center of the scaffold 14 days after seeding. (a) S100β, (b) vimentin. (c) Collagen structure visualized by SHG. (d) Merge. This example of Perimaix prototype S1 served as a growth permissive niche for hSCs; cells expressed the classical SC markers vimentin and S100β, adhered to the collagen walls as well as to each other, and oriented along the microchannels (channel-orientation indicated by the white arrow), adopting a bipolar morphology typical for SCs. Scale bar 50 μm.
