The Role of CTLA-4 Exon-1 49 A/G Polymorphism and Soluble CTLA-4 Protein Level in Egyptian Patients with Behçet's Disease

Table 2

Comparisons of allele and genotype frequencies of CTLA-4 +49A/G polymorphism in patients with Behçet’s disease and healthy controls.

CTLA-4 49 A	Genotypes frequency, 𝑛 (%)			Alleles frequency, 𝑛 (%)
	AA	AG	GG	A	G
Patients (𝑛=60)	31 (51.7)	21 (35.0)	8 (13.3)	83 (69.2)	37 (30.8)
Controls (𝑛=95)	21 (22.1)	38 (40.0)	36 (37.9)	80 (42.1)	110 (57.9)
𝑃 value	<0.001*	0.056		<0.001*
OR	6.643	2.487		3.084
CI (95%)	2.58–17.10	0.98–6.32		1.90–4.99

^∗𝑃 value is significant <0.05, 𝜒²: chi-square, OR: odds ratio, and CI: confidence interval.