Therapeutic Potential of Tacrolimus on Acute Myocardial Infarction in Minipigs: Analysis with Serial Cardiac Magnetic Resonance and Changes at Histological and Protein Levels
Figure 7
Western blotting for assessing protein expressions of apoptotic biomarkers including Bax (a), (b) and Csp-3 (c), (d), and DNA damage biomarker c-PARP (e), (f) in normal remote myocardium, infarct, and peri-infarct areas of both groups. Note the significantly lower expressions of Bax, Csp-3, and c-PARP in normal than in controls and tac-treated animals (* versus other groups, all ), and significantly higher expressions of these biomarkers in controls than in tac-treated animals († versus ‡, all ) (a)–(f).