Synthesis and Characterization of Folate-Targeted Dextran/Retinoic Acid Micelles for Doxorubicin Delivery in Acute Leukemia

<table>Flow cytometry results to analyze the cellular uptake of (a) negative control (culture medium), (b) blank of nontargeted muscles of RA/DEX, (c) blank of targeted muscles of FA-RA/DEX, (d) free doxorubicin HCl (0.754 <i>μ</i>g/mL), (e) nontargeted RA/DEX micelles (containing 0.754 <i>μ</i>g/mL doxorubicin HCl), and (f) targeted RA/DEX micelles (containing 0.754 <i>μ</i>g/mL doxorubicin HCl). The percentage of viable cells is presented in each image which is computed from the obtained values for the gated cells.</table>

BioMed Research International

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Figure 13

Figure 13: Synthesis and Characterization of Folate-Targeted Dextran/Retinoic Acid Micelles for Doxorubicin Delivery in Acute Leukemia 