Human Cytomegalovirus-Encoded miR-US25-1 Aggravates the Oxidised Low Density Lipoprotein-Induced Apoptosis of Endothelial Cells
Figure 2
miR-US25-1 mimics reduced EAhy926 cell viability but did not induce apoptosis in EAhy926 cells. (a) The miR-US25-1 level was promoted by miR-US25-1 mimics, rather than miR control, both of which were transfected in EAhy926 cells with 50 nM. (b) Viability of EAhy926 cells decreased after HCMV infection with 0.1 or 1 MOI (compared to blank), revealed by MTT assay. (c) miR-US25-1 mimics, rather than miRNA control, reduced EAhy926 cell viability, revealed by MTT assay. (d) No significant difference in regulation of apoptosis of EAhy926 cells by the miR-US25-1 mimics and the miRNA control. The results are expressed as percentages of positive mean values S.E. for three independent experiments. (e) Apoptosis of EAhy926 cells with miR-US25-1 mimics or miRNA control transfection of 50 nM. (f) No significant difference in caspase 3 activity in EAhy926 cells after miR-US25-1 mimics or miRNA control transfection. ns: no significance, or , , and .
