Insulin Preconditioning Elevates p-Akt and Cardiac Contractility after Reperfusion in the Isolated Ischemic Rat Heart

Table 1

Baseline measurements.

	Control	Post-Ins	Pre-Ins
Number ()	12	12	12
Rat weight (g)	303 ± 5	301 ± 3	303 ± 5
Dry heart weight (g)	0.24 ± 0.05	0.23 ± 0.02	0.23 ± 0.04
Heart rate (bpm)	248 ± 29	236 ± 35	242 ± 32
dP/dt max (mm Hg/sec)	3197 ± 648	3141 ± 453	3215 ± 653
Coronary flow (mL/min)	12.8 ± 1.8	13.1 ± 2.0	12.8 ± 1.9

Data are mean ± SD. There are no significant differences among the groups by analysis of variance.
Baseline measurements are presented in absolute values as obtained after 10 min stabilization except for dry heart weight which was measured at the end of the experiment.
dP/dt max: maximum of left ventricular derivative of pressure development.