Oxidative Stress and Bone Resorption Interplay as a Possible Trigger for Postmenopausal Osteoporosis

Table 2

OxS markers mean levels in healthy, osteopenic, and osteoporotic postmenopausal women.

	Healthy (𝑛=38)	Osteopenia (𝑛=73)	Osteoporosis (𝑛=56)
Hydroperoxides (CU)	349.3 ± 12.3	352.7 ± 11.7	370.6 ± 10.8
AOPP (𝜇moles/L)	82.1 ± 8.8	76.6 ± 2.9	87.4 ± 7.6
Thiols (𝜇moles/L)	225.9 ± 13.9	215.2 ± 12.7	225.0 ± 17.3
Total antioxidant power (FRAP units)	734.1 ± 28.2	675.7 ± 15.7	697.2 ± 21.6
PON-1 (U/mL)	134.1 ± 9.2	138.2 ± 9.3	122.1 ± 12.2
Ceruloplasmin (mg/dL)	52.6 ± 6.7	49.2 ± 4.0	45.9 ± 5.1

Data presented are expressed as mean ± standard errors for continuous variables.
Abbreviations: AOPP: advanced oxidation protein products; CU: Carratelli Units; FRAP: Ferric reduction antioxidant capacity; PON-1: paroxonase-1.