Oxidative Stress and Bone Resorption Interplay as a Possible Trigger for Postmenopausal Osteoporosis

Table 4

Multiple regression analysis of the association of hydroperoxides and CTX-1 with lumbar spine BMD.

Explanatory variables
	B* (SE)	β ^#
Model 1
Hydroperoxides	0.262^b; (0.061)	−0.321
	Adjusted 𝑅^2=0.25
Model 2
CTX-1	−0.044^a; (0.023)	−0.172
	Adjusted 𝑅^2=0.16
Model 3
Hydroperoxides	−0.246^b; (0.066)	−0.301
CTX-1	−0.026; (0.023)	−0.100
	Adjusted 𝑅^2=0.25

Model 1: age, years since menopause, smoking, waist circumference + hydroperoxides.
Model 2: age, years since menopause, smoking, waist circumference + CTX-1.
Model 3: age, years since menopause, smoking, waist circumference + hydroperoxides and CTX-1.
aP < 0.05; ^bP < 0.01.
∗Unstandardized regression coefficient; ^#standardized regression coefficient.
Abbreviations: SE: standard error; CTX-1: C-terminal telopeptide of type I collagen.