Research Article

rhPDGF-BB Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Stromal Cells from Streptozotocin-Induced Diabetic Rats through ERK Pathway

Figure 4

rhPDGF-BB-induced cell proliferation was inhibited by suppression of ERK pathway. Cells were pretreated with or without 20 μM PD98059 for 1 h and treated with 10 ng/mL rhPDGF-BB. The unmanipulated cells were used as controls. MTT assay was assessed on days 2, 4, and 7. * , versus control, and # , versus 10 ng/mL.
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