Effect of Mesalamine and Prednisolone on TNBS Experimental Colitis, following Various Doses of Orally Administered Iron

Table 4

Differences in histological parameters between group 5 (TNBS + Fe 0.3%) versus group 7 (TNBS + Fe 0.3% + mesalamine) and group 6 (TNBS + Fe 3%) versus group 8 (TNBS + Fe 3% + mesalamine).

Parameter	Group 5 versus 7	𝑃 value	Group 6 versus 8	𝑃 value
Overall histology	4.21±1.77 versus 2.00±0.74	0.000	3.79±1.35 versus 4.67±0.65	0.013
Inflammatory infiltration	1.58±0.72 versus 0.67±0.65	0.001	1.37±0.71 versus 2.42±0.51	0.000
Eosinophilic infiltration	1.54±0.72 versus 1.00±0.00	0.001	1.33±0.48 versus 1.08±0.29	0.061
Edema	1.08±0.72 versus 0.33±0.49	0.003	1.08±0.58 versus 1.17±0.39	0.658