Antiproliferative Activity of the Isofuranonaphthoquinone Isolated from Bulbine frutescens against Jurkat T Cells
Figure 7
The effects IFNQ on drug efflux of the MCB-GSH conjugate from Jurkat T cells as a function of treatment. Cells were incubated with MCB. CDNB (positive control) or the IFNQ was added. Cells were then spun and the supernatant taken to determine the amount of the MCB-GSH conjugate effluxed (a). Cells were also lysed and the amount of MCB-GSH in the cells was also determined (b). Preincubations were performed at 10°C and 37°C. Values are the mean of ± SD for for duplicate measurements ***, **, and *. ***Asterisks in black are differences with the control, whilst those in red are differences between CDNB and IFNQ.
