Abarema cochliacarpos Extract Decreases the Inflammatory Process and Skeletal Muscle Injury Induced by Bothrops leucurus Venom

Figure 2

Effect of A. cochliacarpos extract (EAc) on B. leucurus venom’s mechanical hyperalgesia response. Mice received perimuscular injection of PSS or B. leucurus venom (1 mg/kg). The animals were treated with oral EAc at 100 mg/kg, 200 mg/kg, and 400 mg/kg and i.v. dexamethasone (2 mg/kg) 5 min after venom injection. Results showing the force needed to cause paw withdraw (pain threshold). Data report means ± SEM (𝑛=6). ^∗𝑃<0.05 and ^∗∗𝑃<0.01 versus venom group (Student’s 𝑡-test).