Alterations in Lipid Mediated Signaling and Wnt/β-Catenin Signaling in DMH Induced Colon Cancer on Supplementation of Fish Oil

Figure 3

Downregulation of 15-deoxy PGJ₂ on administration of different ratios of fish oil and corn oil in experimentally induced colon cancer. Chromatogram represents (a) peak of standard 15-deoxy PGJ₂ and (b) peak of test sample. (c) Table depicting the levels of 15-deoxy PGJ₂ in both the initiation and postinitiation phase. The results are expressed as Mean ± S.D. for 𝑛=8. ^∗∗∗𝑃<0.001 with respect to control, ^###𝑃<0.001 with respect to DMH, and ^†††𝑃<0.001 with respect to FO : CO(1 : 1) + DMH.

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