Alterations in Lipid Mediated Signaling and Wnt/β-Catenin Signaling in DMH Induced Colon Cancer on Supplementation of Fish Oil

Table 2

Effect of fish oil and corn oil on PPARγ expression in experimentally induced colon cancer.

Groups	Net MFI of PPARγ
	Initiation phase	Postinitiation phase
Control group	129.33 ± 7.11	148.50 ± 11.22
DMH treated	116.33 ± 7.89	356.83 ± 29.48***
FO : CO (1 : 1) + EDTA	276.83 ± 18.47	153.89 ± 9.32
FO : CO (1 : 1) + DMH	239.60 ± 34.01^###	207.33 ± 13.38^###
FO : CO (2.5 : 1) + EDTA	162.60 ± 8.73	163.00 ± 16.31
FO : CO (2.5 : 1) + DMH	156.33 ± 16.42^###,†††	134.67 ± 8.09^###,†††

The results are expressed as Mean ± S.D. for n = 8.
^∗∗∗𝑃<0.001 with respect to control, ^###P < 0.001 with respect to DMH, and ^†††P < 0.001 with respect to FO : CO (1 : 1) + DMH.