Clinical Study
Significance of Image Guidance to Clinical Outcomes for Localized Prostate Cancer
Table 7
Acute gastrointestinal (GI) and genitourinary (GU) toxicity in the literature on radiation therapy of prostate cancer.
| Study |
Patients () |
Total dose (Gy) |
Fractions () |
EQD2 (Gy) | IGRT | Acute GI (%) | Acute GU (%) | Grade 2 | Grade 3 | Grade 2 | Grade 3 |
|
Pollack et al. 2006 [7] | 100 | 76 (D95) 70.4 (D95) | 38 28 | 76 84.6 | Daily | 8 18 | 0 0 | 54 40 | 2 8 | Fonteyne et al. 2008 [8] | 230 | 78 (median) | 38 | 79.1 | Daily | 11 | 0 | 41 | 7 | Ghadjar et al. 2008 [54] | 39 | 80 (median) | 40 | 80 | Daily | 3 | 0 | 56 | 8 | Lips et al. 2008 [9] | 331 | 76 (mean) | 35 | 79.7 | Daily | 30 | 0 | 47 | 3 | Marchand et al. 2010 [55] | 55 | 72.2 | 38 | 70.1 | Daily | 12.7 | 0 | 38.2 | 1.8 | Deville et al. 2010 [56] | 30 | 79.2 | 44 | 74.7 | Daily | 13 | 0 | 50 | 0 | Our own data | 127 | 78.6 (mean) | 39 | 78.9 | Customized | 4 | 0 | 17.3 | 0 |
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