Research Article
Frequency of TGF-β and IFN-γ Genotype as Risk Factors for Acute Kidney Injury and Death in Intensive Care Unit Patients
Table 1
Biochemical and epidemiological data according to the development for acute kidney injury (AKI) (
) and healthy individuals (Control) (
).
| | | AKI | Control () | | | | Yes () | No () |
| | Age (years) | 67 ± 17 | 65 ± 18 | 60 ± 10 | 0.67 | | Gender (male) | 91 (66%) | 97 (60%) | 154 (61%) | 0.26 | | APACHE II score | 20 ± 7* | 17 ± 6 | — | <0.05* | | MDRD | 70 ± 51* | 100 ± 49 | 81 ± 13 | <0.05* | | Creatinine (mg/dL) | 1.07 ± 1.20* | 0.40 ± 0.70* | 1.00 ± 0.2 | <0.05* | | Albumin (mg/dL) | 3.06 ± 0.25 | 3.24 ± 0.54 | 4.5 ± 0.3 | 0.22 | | CRP (mg/dL) | 7.89 ± 8.61 | 7.20 ± 8.47 | 0.56 ± 0.69 | 0.48 | | Vasoactive drug | 24 (17%)* | 6 (4%) | — | <0.05* | | Mechanical ventilation | 29 (21%)* | 11 (7%) | — | <0.05* | | Sepsis | 44 (32%)* | 35 (21%) | — | 0.04* | | Coronary arterial disease | 26 (19%) | 31 (19%) | — | 0.96 | | Stroke | 7 (5%) | 13 (8%) | — | 0.31 | | Hypertension | 54 (39%) | 68 (40%) | 73 (29%) | 0.80 | | Diabetes mellitus | 25 (18%) | 31 (19%) | 32 (13%) | 0.83 | | Chronic kidney disease | 1 (0.01%) | 3 (0.02%) | — | 0.60 | | Mortality rate (%) | 12 (9%) | 7 (4%) | — | 0.12 |
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AKI compared to No AKI-Student’s and chi-square test; ANOVA when appropriate.
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