FC-98 Regulates TLR9-Mediated of CXCL-10 Expression in Dendritic Cells via MAPK and STAT1 Signaling Pathway

Figure 4

Effect of FC-98 on BMDCs CXCL-10 expression and function. BMDCs were treated with various concentrations of FC-98 for 2 h, and then 1 𝜇M CpG was added for another 6 h before q-PCR (a) or 24 h before ELISA (b). (c) Transwell experiment was performed to examine the function of pretreated BMDCs on T cells. The data are mean ± SD of three independent experiments. ^##𝑃<0.01; ^###𝑃<0.001 a versus control group; **𝑃<0.01; ***𝑃<0.001 versus CpG only group.

(a)

(b)

(c)