Exploring the miRNA-mRNA Regulatory Network in Clear Cell Renal Cell Carcinomas by Next-Generation Sequencing Expression Profiles

Table 2

Top 15 down-/upregulated sncRNAs in ccRCC tissues.

ncRNA	Control NEV	Cancer NEV	log2 Fold change	FDR
hsa-miR-363-3p	5,076.33	645,08	−2,98	1,2081𝐸−21
hsa-miR-500a-3p	1,289.69	221,65	−2,54	4,1147𝐸−19
hsa-miR-206	291,35	14,45	−4,33	6,3156𝐸−08
hsa-miR-10b-3p	153,08	34,08	−2,17	8,2369𝐸−08
hsa-miR-106a-5p	396,71	64,42	−2,62	2,8155𝐸−07
hsa-miR-135a-5p	1,127.62	82,86	−3,77	5,4484𝐸−07
hsa-miR-660-5p	981,73	158,15	−2,63	1,5614𝐸−06
hsa-miR-3065-5p	77,52	10,24	−2,92	3,8416𝐸−05
hsa-miR-30c-2-3p	12,274.78	4,399.26	−1,48	5,7416𝐸−05
hsa-miR-335-5p	781,07	258,25	−1,60	6,2893𝐸−05
hsa-miR-514a-5p	66,83	0,26	−8,01	6,3893𝐸−05
hsa-miR-129-1-3p	45,12	0,11	−8,64	0,00011999
hsa-miR-216b	402,11	17,60	−4,51	0,00012813
hsa-miR-188-5p	80,69	15,72	−2,36	0,0005944
hsa-miR-362-5p	302,80	62,05	−2,29	0,00087791
ncRNA	Control NEV	Cancer NEV	log2 Fold change	FDR
hsa-miR-584-5p	7,40	37,24	2,33	0,00060831
hsa-miR-590-3p	33,82	158,08	2,22	0,00074439
hsa-sno-ACA61	180,29	693,03	1,94	0,00115355
hsa-miR-142-5p	501,18	1,769.88	1,82	0,00136324
hsa-sno-mgh18S-121	47,08	111,93	1,25	0,00687682
hsa-miR-34a-5p	76,09	383,47	2,33	0,00921823
hsa-sno-ACA52	9,77	28,35	1,54	0,01048507
hsa-miR-106b-3p	294,41	680,87	1,21	0,02347042
hsa-miR-3182	4,33	26,20	2,60	0,03703154
hsa-sno-ACA44	54,31	201,32	1,89	0,05439511
hsa-miR-24-2-5p	127,79	292,76	1,20	0,06507243
hsa-miR-7-5p	439,97	3,243.48	2,88	0,06507243
hsa-miR-210	1,062.71	7,973.01	2,91	0,06507243
hsa-miR-16-2-3p	35,85	123,42	1,78	0,06507243

NEV: normalized expression value; Log2 Fold change: log2[cancer/control ratio]; FDR: corrected 𝑃 value.