Review Article

Serologic Intestinal-Fatty Acid Binding Protein in Necrotizing Enterocolitis Diagnosis: A Meta-Analysis

Table 2

PLR, NLR, DOR, AUC, and value for each stage.

StagePLR (95% CI)NLR (95% CI) DOR (95% CI) AUC

NEC I3.54 (2.29–5.46)0.45 (0.33–0.60)10.42 (2.84–38.28) 0.010.750.69
NEC II4.23 (2.49–7.18)0.33 (0.21–0.51)15.82 (4.37–57.19) 0.000.820.76
NEC III4.49 (2.85–7.09)0.25 (0.15–0.43)21.26 (6.53–69.21) 0.030.910.84

PLR: positive likelihood ratio; NLR: negative likelihood ratio; DOR: diagnostic odds ratios; AUC: area under curve; CI: confidence interval; : the maximum joint sensitivity and specificity.