Subchronic Arsenic Exposure Induces Anxiety-Like Behaviors in Normal Mice and Enhances Depression-Like Behaviors in the Chemically Induced Mouse Model of Depression

Figure 6

The influence of subchronic arsenic exposure on the BDNF levels of serum and cerebral PFC. Eight weeks after exposure to 10 mg/L arsenic or drinking water alone in normal mice and in reserpine pretreated mice, the levels of BDNF protein of serum (a) and cerebral PFC (b) were determined by enzyme-linked immunosorbent assay (ELISA). Each value/error bar is expressed as the mean ± SD of 8 mice. , , significant difference compared with normal control group.

(a)

(b)