Mass Spectrometry in Pharmacokinetic Studies of a Synthetic Compound for Spinal Cord Injury Treatment

Figure 2

Limit of detection in solution for IG20 by MALDI-TOF MS. The mass spectrum for IG20 at 500 pg/μL (a), 250 pg/μL (b), and 100 pg/μL (c) is shown. Below these concentrations the IG20 peak was undetectable from background (d). The sample and DHB matrix in ratio of 1 : 1; the mass peak for IG20 at 550.3 m/z.

(a)

(b)

(c)

(d)