Research Article
MicroRNA181a Is Overexpressed in T-Cell Leukemia/Lymphoma and Related to Chemoresistance
Table 1
Clinicopathological characteristics of 130 patients with T-cell leukemia/lymphoma.
| | Characteristics | High miR181a expression () | Low miR181a expression () | value |
| | Age (years) | | | | | ≥60 | 13 | 17 | 0.5328 | | <60 | 52 | 48 | | Gender | | | | | Male | 42 | 32 | 0.1106 | | Female | 23 | 33 | | Lactic dehydrogenase level (LDH) | | | | | Normal | 19 | 23 | 0.5740 | | Above normal | 46 | 42 | | Pathological subtypes | | | | | T-ALL | 15 | 17 | 0.6656 | | T-LBL | 8 | 8 | | PTCL-NOS | 22 | 23 | | ALCL | 6 | 9 | | AITL | 14 | 8 | | International prognostic index (IPI) | | | | | Low | 12 | 11 | 0.3152 | | Low/intermediate | 23 | 33 | | Intermediate/high | 20 | 15 | | High | 10 | 6 | | Overall response (CR + PR) | 38 | 50 | 0.0385 |
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CR, complete remission; PR, partial remission.
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