Research Article
ProSim: A Method for Prioritizing Disease Genes Based on Protein Proximity and Disease Similarity
Table 3
Fraction of true disease genes.
| | | ProSim | PRINCE | RWR | DADA |
| | Breast cancer | 80% | 77% | 72% | 75% | | Alzheimer’s | 69% | 58% | 55% | 53% | | Colorectal cancer | 66% | 63% | 61% | 62% | | Diabetes mellitus type 2 | 57% | 58% | 53% | 69% | | Lung cancer | 50% | 48% | 42% | 45% | | Prostate cancer | 71% | 61% | 53% | 60% |
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