Alendronate-Eluting Biphasic Calcium Phosphate (BCP) Scaffolds Stimulate Osteogenic Differentiation

Figure 2

Attenuated total Fourier-transform infrared spectroscopy (ATR-FTIR) spectra of (a) ALN, (b) BCP, (c) ALN (0.1 mg)/BCP, and (d) ALN (1 mg)/BCP scaffolds. The characteristic peaks of alendronate sodium appear at 926 cm⁻¹ for the hydroxyl group and at 1020 cm⁻¹ and 1050 cm⁻¹ for P=O (indicated by the arrows), and BCP appears at 940–1120 cm⁻¹, 603 cm⁻¹, and 566 cm⁻¹ for orthophosphate (PO₄) (indicated by the black triangles). These experiments were repeated three times.