High Order Gene-Gene Interactions in Eight Single Nucleotide Polymorphisms of Renin-Angiotensin System Genes for Hypertension Association Study

Figure 3

Epistasis networks of the best 2- to 8-locus models for SNP-SNP interaction are associated with hypertension. Significant gene-gene interactions () in these multifoci models are connected by blue lines, and the strength of interaction is labeled with OR values. The thicker and thinner lines represent the higher and lower interactions, respectively.