Effect of Spirulina Intervention on Oxidative Stress, Antioxidant Status, and Lipid Profile in Chronic Obstructive Pulmonary Disease Patients
Table 5
Effect of spirulina intervention at (500 × 4) mg dose on serum content of oxidants and antioxidants and on the activity of burst enzymes in COPD patients.
Parameters
0 days (mean ± SD)
30 days (mean ± SD)
60 days (mean ± SD)
value
value
Malondialdehyde (MDA) (nmoL/mL)
3.78 ± 0.24
3.11 ± 0.25
2.43 ± 0.28
216.404
0.000*
Lipid hydroperoxide (nmoL/mL)
3.63 ± 0.19
3.10 ± 0.23
2.44 ± .21
240.034
0.000*
Catalase (kU/L)
31.53 ± 8.41
36.12 ± 8.21
42.25 ± 7.59
13.314
0.000*
Superoxide dismutase (SOD) (U/mL)
67.25 ± 6.43
74.76 ± 5.64
80.83 ± 4.89
42.864
0.000*
Glutathione-S-transferase (GST) (U/mL)
28.41 ± 4.02
31.61 ± 3.75
32.88 ± 3.42
11.350
0.000*
Glutathione (GSH) (nmoL/mL)
279.3 ± 23.26
316.76 ± 16.68
356.57 ± 11.71
140.565
0.000*
Vitamin C (mg/dL)
0.76 ± 0.07
0.85 ± .06
0.98 ± .05
114.403
0.000*
Cholesterol (mg/dL)
167.22 ± 10.33
155.28 ± 7.45
140.72 ± 14.90
41.244
0.000*
Triglyceride (TG) (mg/dL)
172.10 ± 14.44
166.50 ± 13.25
161.34 ± 11.68
5.011
0.000*
High density lipoprotein (HDL) (mg/dL)
42.21 ± 5.17
43.16 ± 5.15
44.69 ± 4.79
1.853
0.163
Statistically significant. Comparisons are made between day 0 versus day 30 and day 0 versus day 60.
